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Subgroup analyses indicated reduced risks of colorectal cancer (HR 0.81: 95% CI: 0.680.96) and liver cancer (HR: 0.74

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Cryo-electron microscopy (Cryo-EM) has revealed that integrin v8 can bind to latent TGF- (L-TGF-) and activate TGF-/SMAD signaling without releasing TGF- from its latent complex, providing a novel perspective on pathway activation (Campbell et al